The significance of correlation laboratory examination in esophageal cancer patients before and after operation
10.3969/j.issn.1673-4130.2017.12.012
- VernacularTitle:食管癌患者手术前后血管生成相关实验室指标检测意义研究
- Author:
Meiying WANG
;
Wanjuan GU
;
Rui YANG
;
Zhen ZHANG
;
Qing PAN
- Keywords:
esophageal cancer;
soluble CD105;
TGF-β1;
VEGF
- From:
International Journal of Laboratory Medicine
2017;38(12):1617-1618
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of soluble CD105,transforming growth factor-beta1(TGF-β1) and vascular endothelial growth factor(VEGF) in esophageal cancer(EC) patients,analyzing its clinical significance.Methods Collecting 56 cases of gastric cancer(observation group) and 49 cases of healthy people(control group)from Nov.2014 to Jan.2016 as the research objects.The levels of soluble CD105,TGF-β1 and VEGF were detected in EC patients pre-and post-operation and healthy subjects.The data of soluble CD105,TGF-β1 and VEGF were analyzed in the two groups.Results The pre-operation levels of soluble CD105,TGF-β1 and VEGF in EC patients were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The pre-operation levels of soluble CD105,TGF-β1 and VEGF in EC patients were significantly higher than post-operation levels,the difference was statistically significant(P<0.05).The post-operation levels of soluble CD105,TGF-β1 and VEGF in EC patients were not statistically different with control group(P>0.05).Conclusion The levels of soluble CD105,TGF-β1 and VEGF could be abnormal in patients with EC,which might be the index for monitoring the clinical disease condition and judging the prognosis of the EC.
