Investigation and analysis of human T lymphocyte virus infection in blood donors in Zhongshan area of Guangdong
10.3969/j.issn.1673-4130.2017.12.016
- VernacularTitle:广东中山地区献血人群人类嗜T淋巴细胞病毒感染状况调查
- Author:
Ruihong HE
;
Wensheng YUAN
;
Zongwei ZHAN
;
Feng YI
;
Yanhuan HE
;
Ainong SUN
;
Huiyan LIN
- Keywords:
human T lymphocyte virus;
infection;
blood donors
- From:
International Journal of Laboratory Medicine
2017;38(12):1628-1629,1633
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the infection situation of human T lymphocyte virus(HTLV) among blood donors in Zhongshan area.Methods Blood samples from 40 874 blood donors in Zhongshan from March to December 2016 were screened for HTLV antibody by using,enzyme linked immunosorbent assay(ELISA).The positive samples were reexamined two times,and specimens with positive results of reexamination were detected by using immunohistochemical method(CLIA).Then the positive samples were confirmed by Western blot(WB),and confirmed positive samples were judged as infection.Results Of all 40 874 cases of voluntary blood donors,21 cases were positive with HTLV antibody detected by ELISA,the positive rate of ELISA was 0.05%.Five cases were positive detected by CLIA method.One case was confirmed by WB,and the infection rate was 0.002 4%.Conclusion In order to ensure the safety of blood transfusion and reduce blood transfusion infection of HTLV,it might be necessary to perform HTLV screening in first-time blood donors in Zhongshan area.
