A correlated study between-L-alpha glucosidase and intrauterine growth and glucose and lipid metabolism in fetus below the gestational age
10.3969/j.issn.1006-5725.2017.10.019
- VernacularTitle:α-L-岩藻糖苷酶与小于胎龄儿宫内发育及其糖脂代谢的相关性
- Author:
Wenbin DONG
;
Xiaopin LEI
;
Lingpin ZHANG
;
Lianyu ZHANG
;
Na HE
- Keywords:
Small for gestational age;
Alpha-L-fucosidase;
Blood lipid;
Blood glucose
- From:
The Journal of Practical Medicine
2017;33(10):1605-1607
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of serum alpha-L-fucosidase(AFU)and its correlation with the blood glucose and lipid level in small for gestational age(SGA)fetuses. Methods 125 SGA fetuses and 128 fetuses in appropriate for gestational age(AGA)with wet lung were treated in our hospital and were investigated as case control study. The serum of AFU ,blood glucose and lipid were measured and compared within 24 hours after birth in these 2 groups. Results Comparing with the AGA infants ,the SGA babies had lower level of serum AFU,high density lipoprotein,apolipoprotein A and apolipoprotein B(P<0.05). The correlation analysis showed that the serum AFU level has positive correlation with blood glucose,total cholesterol,high density lipoprotein, low density lipoproteinand apolipoprotein A(P < 0.05),while it has negative correlation with serum triglycerides in SGA(P<0.05). Conclusions The SGA infants have lower level of serum AFU and lipid metabolic disorders after birth,and its serum AFU level has correlation with its blood glucose and lipid level.
