Clinical value of CT pulmonary angiography combined with pulmonary ventilation perfusion imaging in reducing recurrence rate of pulmonary embolism
10.3969/j.issn.1006-5725.2017.10.031
- VernacularTitle:预测CT肺动脉造影联合肺通气灌注显像检查降低肺栓塞复发率的临床价值
- Author:
Qiongfang YANG
;
Qiaoyng JI
;
Lanyan ZHAO
;
Lanfang FENG
- Keywords:
Pulmonary embolism;
CT pulmonary angiography;
pulmonary ventilation perfusion imag-ing;
recurrence rate
- From:
The Journal of Practical Medicine
2017;33(10):1647-1650
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of CTPA combined with V/Q imaging to guide the end point of anticoagulant therapy in reducing the recurrence rate of pulmonary embolism. Methods A total of 159 cases of pulmonary embolism diagnosed by CTPA were randomly divided into experimental group(n=80)and control group(n = 79). After the regular low molecular weight heparin and warfarin anticoagulation therapy ,the experimental group used the CTPA combined with V/Q imaging to evaluate the pulmonary embolism absorption ,to guide the end point of anticoagulant therapy and to evaluate the recurrence rate of pulmonary embolism at the end of 1-year treatment. But in control group ,only CTPA was used to guide the treatment and then the recurrence rate in 2 groups was compared. Results The anticoagulant treatment course of experimental group was(5.90 ± 1.80) months,which was significantly longer than that of control group(3.57 ± 1.09)months(P<0.05). The recurrence rate of experimental group was significantly lower than that of control group(7.5%vs. 22.8%)after 1-year treatment (P<0.05). However,there was no significant difference between 2 groups(8.75%vs 3.80%)in the rate of bleed-ing during anticoagulation therapy (p>0.05).Conclusions CTPA combined with V/Q imaging to guide the end point of anticoagulant therapy for pulmonary embolismhas important clinical value in reducing the recurrence rate of pulmonary embolism.
