An analysis on set-up errors by data of mugavoltage fan-beam computed tomography during intensity-mod-ulated radiotherapy for nasopharyngeal carcinoma
10.3969/j.issn.1006-5725.2017.09.033
- VernacularTitle:基于断层调强放射治疗中扇形束兆伏级CT数据分析鼻咽癌的摆位误差
- Author:
Fangzheng WANG
;
Chuner JIANG
;
Shuangyan YANG
;
Huanhuan YU
;
Min XU
;
Jianfang SHI
;
Zhenfu FU
- Keywords:
Nasopharyngeal neoplasm;
Megavoltage computed tomography;
Setup error;
Planning target volume;
Tomotherapy
- From:
The Journal of Practical Medicine
2017;33(9):1490-1493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the inter-fraction setup errors and affecting factors from data of daily fan-beam megavoltage computed tomography(MVCT). Methods A total of 37consecutive NPC patients treated with tomotherapy were hospitalized during the period of February 2015 to September 2015. For each patient,one MVCT scan was obtained after conventional positioning ,online correction and tomotherapy delivery daily ,and the scans were put into the planning computed tomography to determine inter-fraction setup errors. The MPTV was calculated with the equation:MPTV=2.5∑+0.7σ(∑:systematic error;σ:random error). Results The average absolute errors of the inter-fraction were(2.102 ± 0.0406)mm,(1.490 ± 0.0348)mm,(1.306 ± 0.335)mm and(1.392 ± 0.0384)° at three dimensions. The total MPTV accounting for inter-error was 3.4675 mm,2.9795 mm,and 2.8885 mm. Gradual increases in both inter-fraction three-dimensional displacement were observed with time and treatment(P < 0.05). Univariate analysis revealed that weight loss and retraction of neck lymph nodes were affecting factors of set-up errors. Conclusions 3 mm margins uniformly expended from clinical target volume to planning target volume may not be suitable. The personalized margin should be adopted for the design of IMRT planning. Displacement increases as a treatment course is prolonged.
