Impact of parathyroidectomy on carotid-femoral pulse wave velocity in hemodialysis patients
10.3969/j.issn.1006-5725.2017.10.005
- VernacularTitle:甲状旁腺切除对血液透析患者颈-股动脉脉搏波速度的影响
- Author:
Gang ZHOU
;
Ping BAO
;
Hongbin MOU
;
Bo GAO
;
Changhua LIU
- Keywords:
Hemodialysis;
Secondary hyperparathyroidism;
Parathyroidectomy;
Pulse wave velocity
- From:
The Journal of Practical Medicine
2017;33(10):1551-1554
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of total parathyroidectomy(tPTX)on carotid-femoral pulse wave velocity(cfPWV)in hemodialysis patients. Methods A total of 35 patients undergoing hemodialysis with refractory secondary hyperparathyroidism and treated with tPTX were studied. Before tPTX and 1 year after the oper-ation,cfPWVwas measured and hepatic and renal function,serum calcium,serum phosphorus,intact parathyroid hormone and hemoglobin were measured. The impact of tPTX on cfPWV in hemodialysis patients was analyzed. Results Serum calcium,serum phosphorus and intact parathyroid hormone decreased(P < 0.01),while hemo-globin and serum albumin increased(P < 0.01)and cfPWV decreased 1 year after the operation,which showed statistical significance(P<0.01). The cfPWV of the patients with tPTX was still higher than that of healthy indi-viduals(P<0.01). Conclusion tPTX can effectively reduce cfPWV in hemodialysis patients with refractory sec-ondary hyperparathyroidism.
