Correlation between MR lacune of presumed vascular origin and microalbuminuria and in elderly patients
10.3969/j.issn.1006-5725.2017.10.030
- VernacularTitle:老年患者头颅MR腔隙灶改变与尿微量白蛋白的相关关系及其危险因素的探讨
- Author:
Shuangyan WANG
;
Qingchun GAO
;
Qinbao QIN
- Keywords:
Lacune of presumed vascular origin;
Microalbuminuria;
Cerebral small vessel diseases;
Elderly patients
- From:
The Journal of Practical Medicine
2017;33(10):1642-1646
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of lacune of presumed vascular origin and microalbu-minuria in elderly inpatients. Methods 237 elderly patients (184 males and 53 females) at Guangzhou First People's Hospitalwho aged from 70 to 94 years old with a median age of 83.92 ± 5.32 were included in this study. We collected data on age,gender,medical history,smoking history,renal function test,blood lipid test,C-reactive protein,microalbuminuria,cerebral MR. Logistic regression was conducted to analyze all the data. Based on the MR findings ,the patients were divided into two groups:a group with lacune of presumed vascular origin (132 patients)and a control group(105 patients). Results The group with lacune of presumed vascular origin had higher mean systolic blood pressure than the control group. Median MAU was higher in the groupwith lacune of presumed vascular origin.Single factor or multiple factors logistic regression showed that increased systolic blood pressure and positive rates of MAU and MAU were independent risk factors for lacune of presumed vascular origin and were also significantly associated with the severity of lacune of presumed vascular origin. Conclusion Microalbuminuria is significantly associated with lacune of presumed vascular origin in elderly patients.
