Research of curative effect in patients with prostate cancer by 125I implantation with endocrine therapy
10.3969/j.issn.1006-5725.2017.09.027
- VernacularTitle:碘125粒子近距离照射联合内分泌疗法治疗前列腺癌
- Author:
Ruiqian LI
;
Bin ZHAO
;
Yu BAI
;
Hong YANG
;
Yonghong LEI
;
Qilin WANG
- Keywords:
Prostate cancer;
125I implantation;
Endocrine therapy
- From:
The Journal of Practical Medicine
2017;33(9):1468-1471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the curative effect in patients with prostate cancer by 125I implantation with endocrine therapy. Methods Sixty cases of patients with prostate cancer were divided into the experiment group (30 cases) and the control group (30 cases) with or without 125I implantation. The control group were treated by endocrine therapy, the experiment group were treated by 125I implantation based on endocrine therapy. The curative effect were observed. Results The volume of prostate inthe experiment group after 6 month treatment were smaller than that in the control group (P<0.05);The KPS score in the experiment group after 1, 3, 6 months treatment were higher than that of the control group (P<0.05);The level of PSAin the experiment group after 1, 3, 6, 12 months treatment were lower than that in the control group (P<0.05). The total effect in the experiment group after 6, 12 month treatment were higher than that in the control group (P<0.05). There had no significant difference on the survival rate after 1, 2, 3 years treatment in the two groups (P>0.05). Conclusion It has significant efficacy in patients with prostate cancer by 125I implantation with endocrine therapy which can improve the level of PSA and KPS scores. The long-term survival situation is satisfactory. This method is worth of generalization in clinic.
