Platelet-to-lymphocyte ratio and the prognosis of diabetic ketoacidosis
10.3760/cma.j.issn.1671-0282.2017.06.019
- VernacularTitle:血小板/淋巴细胞比值与糖尿病酮症酸中毒预后
- Author:
Wei LI
;
Yingli HU
;
Xiaoping XING
;
Yuxiu LI
;
Huadong ZHU
;
Xuezhong YU
- Keywords:
Platelet-to-lymphocyte ratio;
Diabetes mellitus;
Diabetic ketoacidosis;
Prognosis;
Inflammatory markers;
Emergency room;
Mechanical ventilation;
Organ dysfunction
- From:
Chinese Journal of Emergency Medicine
2017;26(6):693-696
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of platelet-to-lymphocyte ratio (PLR) in the prognosis prediction of patients with diabetic ketoacidosis (DKA).Methods Total of 105 patients with DKA who were treated in resuscitation room of Peking Union Medical College Hospital from January 1,2006 to December 31,2015 were reviewed.Among them,there were 8 cases died,and the other 97 cases survived.Another 105 patients with diabetes mellitus who were treated in the ward of Endocrinol ogy Department in the same period were selected as non DKA control group.The clinical characteristics of the patients in each group were compared and Logistic regression analysis was performed on the prognosis of DKA.Results Mechanical ventilation,simultaneous other organ dysfunction,PLR,Glasgow coma score related to prognosis of DKA (P < 0.05).The OR value of platelet-to-lymphocyte ratio was 3.242.The optimal cutoff value of PLR for predicting the prognosis of patients was 256.50.Its sensitivity and specificity were 87.5% and 88.7%,respectively.Conclusions PLR can be used as a sensitive indicator to predict the prognosis of DKA patients.