Inflammatory myofibroblastic tumor of long bone:a clinicopathologic analysis and review of literatures
10.13315/j.cnki.cjcep.2017.05.014
- VernacularTitle:长骨炎症性肌纤维母细胞性肿瘤的临床病理观察
- Author:
Lihua GONG
;
Weifeng LIU
;
Xiaoqi SUN
;
Ming ZHANG
;
Yi DING
;
Xiaoyuan HUANG
- Keywords:
inflammatory myofibroblastic neoplasm;
bone;
immunophenotypes;
diagnosis;
differentiate
- From:
Chinese Journal of Clinical and Experimental Pathology
2017;33(5):534-538
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To study the clinicopathologic features of inflammatory myofibroblastic tumor (IMT) of long bone.Methods HE and immunohistochemistry of EnVision two-step were used to observe the clinical,radiological,histological and immunophenotype features of IMT of bone.The literatures were reviewed.Results 4 cases of IMT of bone were respectively located in the tibia (2 cases) and femur (2 cases).Histologically,the lesions were characterized by collagen-rich and spindled to plump myofibroblast-like cells and a variable admixture of inflammatory cells.Immunohistochemical study showed that the vimentin,SMA,actin,H-caldesmon and CD34 were positive.Conclusion The IMT is a rare and locally aggressive tumor.The diagnosis should combine the histological characters with immunohistochemical results and should be differentiated from the other tumors and tumor-like lesions.
