Clinical efficacy of sentinel lymph node biopsy for oral cancer: A systematic review
10.3969/j.issn.1001-3733.2017.01.012
- VernacularTitle:口腔癌前哨淋巴结活检价值的系统评价
- Author:
Liming HE
;
Qiang GUO
;
Yongwen HE
- Keywords:
Oral cancer;
Sentinel lymph node;
Biopsy;
Systematic review
- From:
Journal of Practical Stomatology
2017;33(1):54-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical sensitivity and specificity of sentinel lymph node biopsy (SLNB) for oral cancer.Methods:By searching Medline,CENTRAL,EMBSE,CBM,CNKI,WANFANG,etc,an studies about SLNB for the patients with oral cancer array for lymph node metastasis were retrieved.The quality of included studies was evaluated by QUADAS items.The data were analyzed by statistic software Meta-DiSc 1.4.Results:25 studies including 934 subjects were analyzed in the current systematic review.The pooled values of sensitivity,specificity were 91％ (95％ CI 88％-94％) and 100％ (95 ％ CI 99％-100％) respectively.The area under summary receiver operating characteristic (SROC) curve (AUC) of SLNB for cervical lymph node metastasis was 0.99.Conclusion:SLNB procedure has high sensitivity and specificity in the diagnosis of cervical lymph node metastasis,it can be used as an useful method for cervical lymph node metastasis screening in patients with oral cancer.
