Clinical application of G-lipopolysaccharides detection in patients with traumatic brain injury
10.3969/j.issn.1673-4130.2017.11.011
- VernacularTitle:G-脂多糖检测在创伤性脑损伤患者中的临床应用研究
- Author:
Qiangsheng FENG
;
Xiaoqing HA
;
Junhua PENG
;
Yuejuan SONG
;
Qijie QING
;
Xiaohong ZHU
- Keywords:
traumatic brain injury;
G-lipopolysaccharides;
infection
- From:
International Journal of Laboratory Medicine
2017;38(11):1471-1472
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the application value of G-lipopolysaccharides(G-LPS) detection in patients with traumatic brain injury(TBI).Methods From Jan.2013 to Jun.2014,plasma G-LPS of TBI-patients and non-patients in this hospital were detected by using MB-80 microbiology analyzer and compared.Results of pathogenic microbiological detection of G-LPS positive TBI patients were analyzed,and G-LPS levels,detected before and after treatment,were also analyzed.Results G-LPS positive rate of TBI patients(33.33%) was higher than the 13.34% of non-TBI patients(P<0.05).After treatment,G-LPS level in G-LPS positive TBI patients significantly decreased(P<0.05).The common pathogenic bacteria,causing infection in TBI patients,included Acinetobacter bauman,Klebsiella pneumoniae and Escherichia coli,and the most common infection diseases included respiratory tract infections and urinary tract infections.Conclusion G-LPS detection could be used for the early detection of secondary infection in TIB patients,with significance for guiding clinical treatment.
