Clinical and pathological influence of high uric acid on idiopathic membranous nephropathy

VernacularTitle:高尿酸血症对特发性膜性肾病临床及病理的影响
Author: Aifang HUANG ; Juan WANG ; Qian PENG ; Wei LI
Keywords: High uric acid; Idiopathic Membranous Nephropathy; Clinical and pathological
From: The Journal of Practical Medicine 2017;33(8):1227-1230
CountryChina
Language:Chinese
Abstract: Objective To study the clinical and pathological influence of high uric acid on idiopathic membranous nephropathy (IMN) Methods A retrospective study with 314 patients diagnosed with IMN from January 2014 to June 2016 was conducted and the clinical pathological influence of high uric acid on IMN was analyzed.Results (1) Of the total,the prevalence of hyperuricaemia patients was 23.2％ (73 cases);(2) The difference of age,course of the disease,blood pressure and symptoms between hyperuricaemia IMN patients and IMN patients with normal uric acid was statistically significant (P ＜ 0.05);(3) Laboratory test indexes such as blood lipid and renal function between hyperuricaemia IMN patients and IMN patients with normal uric acid indicated statistical significance (P ＜ 0.05);(4) The pathological damage was aggravated in hyperuricaemia IMN patients (P ＜ 0.05).Conclusion High uric acid can enhance the clinical and pathological damage of IMN,and comprehensive and effective treatments should be conducted to delay the development of disease.