Roles of 99mTc-MDP and SPECT/CT fusion imaging in the diagnosis and treatment decisions of bone metastasis of malignant tumors
10.3969/j.issn.1006-5725.2017.08.036
- VernacularTitle:99mTc-MDP SPECT/CT融合骨显像在恶性肿瘤骨转移诊断和治疗决策中的作用
- Author:
Jiachen LIU
;
Xiaofeng LIN
;
Jingyan LI
;
Hong ZHANG
;
Jiugen LIANG
;
Xianping LU
;
Zhanlei ZHANG
;
Sheng LIU
- Keywords:
Bone metastases;
Treatment plan;
SPECT/CT bone fusion imaging;
Whole body bone scintigraphy;
Anatomical imaging
- From:
The Journal of Practical Medicine
2017;33(8):1331-1334
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of (99)Tc(m)-MDP SPECT/CT bone fusion imaging in diagnosis and treatment strategy establishment of patients with bone metastatic malignancy.Methods Retrospective study was carried out on 66 patients (55 patients with primary malignant tumors,11 patients with primary benign bone disease) chosen from 117 patients who had undergone whole body bone scintigraphy and SPECT/CT fusion imaging examination.Comparison was carried out on diagnostic efficacy for bone metastases and changes of treatment between SPECT/CT fusion imaging and other anatomical imaging (CT and/or MR).Cases excluded are extensive bone metastases and no final diagnosis of patients.Results For diagnosis of patient with bone metastasis and bone metastasis lesion,the sensitivity of SPECT/CT fusion imaging was (90.62％,93.88％),specificity (79.41％,89.47％) and accuracy (84.84％,90.97％),while sensitivity of simple anatomical imaging was (59.38％,51.02％),specificity (94.11％,94.73％) and accuracy (77.27％,79.86％),with a significant difference (P ＜ 0.05).SPECT/CT fusion imaging changed 30.31％ (20/66) the patient's treatment plan,while 16.67％ (11/66) for simple anatomical imaging,with a significant difference (P ＜ 0.05).Conclusions SPECT/CT fusion imaging could increase the accuracy of diagnosis of bone metastases and have an important role in establishing the treatment strategy.
