Clinical Observation of Kangfuxin Solution Combined with Intense Pulsed Light in the Treatment of Rosacea
10.6039/j.issn.1001-0408.2017.17.26
- VernacularTitle:康复新液联合强脉冲光治疗玫瑰痤疮的临床观察
- Author:
Caixia HU
;
Guoqiang ZHANG
;
Yu CUI
;
Liang CHANG
;
Bingjie HUO
;
Ying WANG
;
Shunqiang GAO
- Keywords:
Kangfuxin solution;
Intense pulsed light;
Rosacea;
Treatment effect;
Safety
- From:
China Pharmacy
2017;28(17):2399-2402
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe effects and safety of Kangfuxin solution combined with intense pulsed light in the treat-ment of rosacea. METHODS:A total of 50 rosacea patients in our hospital during May 2014-Jun. 2016 were divided into control group(25 cases)and observation group(25 cases)according to random number table. Based on oral administration of Metronida-zole tablets,control group received intense pulsed light. Observation group was additionally given Kangfuxin solution for local wet compress after 4 to 6 layers of gauze saturated with liquid,5-10 min,qn. Both groups received treatment for 4 weeks. Clinical effi-cacies,as well as symptom score and DLQI score were compared between 2 groups before and after treatment,and the occurrence of ADR was recorded. RESULTS:The response rate of observation group was 92.0%,which was significantly higher than 64.0%of control group,with statistical significance (P<0.05). Before treatment,there was no statistical significance in erythema,pap-ules,pustules,itching,telangiectasia score and total score,DLQI score with before treatment(P>0.05). After treatment,erythe-ma,papules,pustules,itching,telangiectasia score and total score,DLQI score of 2 groups were decreased significantly,and the observation group was significantly lower than the control group,with statistical significance(P<0.05). The incidence of ADR in observation group was 16.0%,which was significantly lower than 40.0% in control group,with statistical significance(P<0.05). CONCLUSIONS:Kangfuxin solution combined with intense pulsed light show significant efficacy for rosacea,and can effectively improve erythema,papules,pustules,itching and telangiectasia,and improve the quality of life with good safety.
