Impact of Severe Cyanosis on Early Post-operative Recovery in Pediatric Patients With Corrective Operation of Tetralogy of Fallot
10.3969/j.issn.1000-3614.2017.06.017
- VernacularTitle:术前严重紫绀对法乐四联症根治术后早期恢复的影响
- Author:
Tuo PAN
;
Xiaofeng WANG
;
Xu WANG
;
Zhongyuan LU
;
Juxian YANG
;
Shengli LI
- Keywords:
Tetralogy of Fallot;
Cyanosis;
Cardiac surgery
- From:
Chinese Circulation Journal
2017;32(6):603-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between pre-operative severe cyanosis (SC) and the early post-operative recovery in pediatric patients with corrective operation of Tetralogy of Fallot (TOF) Methods: A retrospective cohort study was conducted in 271 pediatric TOF patients who received corrective operation in our hospital from 2010-03-01 to 2013-03-01. Based on pre-operative hemoglobin≥180g/L, the patients were divided into 2 groups: SC group,n=48 and Non-SC group,n=223. Univariate analysis was performed to compare the differences between 2 groups; binary Logistic regression analysis was carried out to identify significant changes which was defined byP<0.01 in univariate analysis. Results: Univariate analysis indicated that compared with Non-SC group, the patients in SC group had the higher incidence of post-operative complications,P<0.001, longer time to reach negative fluid balance,P=0.006 and prolonged mechanical ventilation time,P=0.001; while the post-operative kidney injury was similar between 2 groups,P=0.036. Binary Logistic analysis presented that the patients in SC group needed prolonged mechanical ventilation time (OR=3.432, 95% CI 1.014-5.978,P=0.015), longer time to reach negative fluid balance (OR=4.823, 95% CI 2.586-8.941,P=0.002), the higher incidence of post-operative complications (OR=14.322, 95% CI 7.114-26.251,P<0.001). Conclusion: Pediatric TOF patients with pre-operative SC had the higher incidence of early post-operative complications, prolonged mechanical ventilation time and longer time to reach negative fluid balance those resulting delayed post-operative recovery.
