Clinical Significance of Mean Platelet Volume Variation in Acute Pancreatitis and Its Value in Evaluation Therapeutic Effect

VernacularTitle:平均血小板体积变化在急性胰腺炎中的临床意义及治疗效果评估价值
Author: Mengran ZHANG ; Mei ZHANG ; Shuchun SUN
Keywords: Acute pancreatitis; Mean platelet volume; Platelet parameters
From: Journal of Medical Research 2017;46(5):136-140
CountryChina
Language:Chinese
Abstract: Objective To investigate the possible role of mean platelet volume and its value as a therapeutic effect in acute pancreatitis (AP).Methods Data of 78 cases of AP and 40 cases of negative control were retrospectively analyzed.Mean platelet volume (MPV),platelet counts (PLT),platelet distribution width (PDW),leucocyte count (WBC),C reactive protein (CRP) and serum level of calcium (Ca2+) were measured and analyzed on the admission day,3th,5th and 7th day.Results The MPV values were elevated obviously in AP group on the admission day.Moreover,the MPV values of SAP group were significantly higher than those of MAP group on the admission day.The MPV values were decreased at 5 days and 7 days after admission followed by a increasing at 3 days in SAP group.Furthermore,the MPV value of SAP group at every time point was significantly higher than those of MAP group.The MPV values of AP patients showed a significant reduce after treatment.Conclusion MPV was associated with the severity and the treatment effect of acute pancreatitis.