Study on object,verbal and space working memory in male patients with alcohol dependence

VernacularTitle:男性酒依赖患者客体、语音及空间工作记忆研究
Author: Jing DAI ; Liangshuang YIN ; Liangjun PANG ; Haiqin XU
Keywords: Alcohol drinking; Working memory; Neuropsychology
From: Chinese Journal of Behavioral Medicine and Brain Science 2017;26(5):431-434
CountryChina
Language:Chinese
Abstract: ObjectiveTo explore working memory in male patients with alcohol dependence.Methods50 male patients with alcohol dependence(AD group) and 50 healthy controls(HC group) were assessed by digit span test,trail making test and verbal fluency test.The visual-object,visual-verbal,visual-space working memory tasks were used to measure the difference of working memory between the two groups.ResultsCompared with HC group,alcohol dependence group showed significant impairments in performance of error number of visual-object,visual-verbal,visual-space working memory tasks (AD group:(3.76±2.20),3(2,5),(3.74±2.40));(HC group:(2.94±1.60),2(1,3),2(1,4))(t=2.133,P=0.035;Z=-2.400,P=0.016;Z=-2.654,P=0.008).Moreover,scores of Michigan alcoholism screening test were positively correlated with the error number of verbal working memory task (r=0.371,P=0.008).ConclusionThe male patients with alcohol dependence exhibit impairments in all aspects of working memory.