Molecular mechanism and Chinese medicine intervention of liver regeneration
10.3760/cma.j.issn.1007-8118.2017.05.022
- VernacularTitle:肝再生分子机制及中药干预研究进展
- Author:
Lina XU
;
Jinyong PENG
- Keywords:
Liver regeneration;
Molecular mechanisms;
Hepatocyte proliferation;
Chinese herbs
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(5):357-360
- CountryChina
- Language:Chinese
-
Abstract:
Partial hepatectomy (PH) is an effective method for the treatment of various liver tumors,and liver regeneration dysfunction is one of the most serious complications.Therefore,liver regeneration (LR) after PH is particularly important.In this paper,we reviewed the molecular mechanisms of LR including cellular factors,growth factors,metabolism and related signaling pathways,and reviewed the research progresses of the traditional Chinese medicine (TCM) in promoting liver regeneration.The aim was to further clarify the mechanism of the occurrence and development of LR,and to provide valuable information for the development of drugs for treating liver regeneration disorders.
