Laparoscopic radical cholecystectomy vs open surgery for T2 gallbladder cancer
10.3760/cma.j.issn.1007-631X.2017.05.004
- VernacularTitle:T2期胆囊癌腹腔镜胆囊切除术及根治术的可行性分析
- Author:
Lingfu ZHANG
;
Chunsheng HOU
;
Zhi XU
;
Limei GUO
;
Liyuan TAO
;
Xiaofeng LING
;
Lixin WANG
;
Dianrong XIU
- Keywords:
Gallbladder neoplasms;
Cholecystectomy,laparoscopic
- From:
Chinese Journal of General Surgery
2017;32(5):389-392
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate laparoscopic radical cholecystectomy for T2 gallbladder cancers.Methods A retrospective analysis was made on 44 patients with pathology confirmed T2 gallbladder cancer undergoing laparoscopic vs open radical cholecystectomy.The clinicopathological and follow-up data were compared.Results Laparoscopic cholecystectomy was performed in 32 patients,the implantation metastasis rate of this approach has no statistical differences compared with the open cholecystectomy (P =1.000).26 patients underwent laparoscopic radical resection and the remaining 18 patients underwent open radical resection.There was no statistical difference in operation time (P =0.953),blood loss (P =0.193)and postoperative complications (P =1.000),but the laparoscopic radical resection group is superior to the open group on postoperative pain grading (P =0.022),ambulation time (P =0.000),nothing per mouth time (P =0.000) and length of hospital stay (P =0.048).The mean number of lymph nodes retrieved was 5 ±4 (range 1-12) in the laparoscopic radical group and 6 ± 3 (range 1-12) in the open group (P =0.983);the 1,3,5 year survival rates was 92.3%,70.3%,61.5% and 92.3%,76.3%,69.3%,respectively(P =0.473).Conclusions Initial laparoscopic cholecystectomy does not increase the rate of seeding metastasis in the context of intact gallbladder carcinoma.Totall laparoscopic radical resection is feasible in selected T2 gallbladder cancer patients.