Clinicopathological features of para-aortic lymph node metastases in patients with gallbladder cancer
10.3760/cma.j.issn.1007-8118.2017.05.009
- VernacularTitle:胆囊癌腹主动脉旁淋巴结转移患者的临床病理特征
- Author:
Jianbo LI
;
Xuanfu PENG
;
Pan ZHAO
;
Shunhu JIA
- Keywords:
Gallbladder carcinoma;
Para-aortic lymph node;
Extended lymphadenectomy;
Radical resection
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(5):317-319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical course and clinicopathological features of para-aortic lymph node metastases in patients with gallbladder cancer.Methods Forty-two patients with gallbladder cancer who underwent radical resection combined with para-aortic lymphadenectomy at the Mianyang Hospital of Traditional Chinese Medicine from January 2001 to December 2013 were retrospectively studied.The survival rates of the para-aortic lymph node metastasis group were compared with the negative para-aortic lymph node group of patients.Para-aortic lymph node metastasis as well as clinical features were correlated with survival.Results No one died within the perioperative period.The total complication rate was 24.0%,and there was no significant difference between the positive para-aortic lymph node group and the negative group (P >0.05).The rate of para-aortic lymph node metastasis on histopathology was 21.4% (9/42),which was positively correlated with tumor depth of invasion and negatively correlated with the degree of differentiation (P < 0.01).The 1-,2-,and 3-year survival rates of the positive para-aortic lymph node group were significantly inferior to the negative group (P < 0.05).Conclusions Dissection of para-aortic lymph nodes in patients with gallbladder cancer was safe and feasible.Lymphadenectomy did not improve the longterm survival rates of patients with para-aortic lymph node involvement metastases.The extent of lymph node dissection for gallbladder cancer should be decided by intraoperative biopsy.