Cognitive impairment after ischemic stroke: pathophysiological mechanisms and predictors
10.3760/cma.j.issn.1673-4165.2017.03.013
- VernacularTitle:缺血性卒中后认知损害:病理生理学机制和预测因素
- Author:
Yuexinzi JIN
;
Yun XU
- Keywords:
Stroke;
Brain Ischemia;
Cognition Disorders;
Dementia;
Vascular;
Inflammation;
Amyloid β-Peptides;
Blood-Brain Barrier;
Neuronal Plasticity;
Biomarkers;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2017;25(3):263-267
- CountryChina
- Language:Chinese
-
Abstract:
Cognitive impairment caused by ischemic stroke is becoming more and more concerned.It is crucial to explore its pathophysiological mechanism and related clinical predictive indexes for understanding the occurrence,development and treatment of the disease.This article discusses the pathophysiologic mechanism of cognitive impairment after stroke from the aspects of white matter damage,amyloid abnormal deposition,blood-brain barrier damage,and synaptic plasticity injury,and reviews the risk factors,imaging and biological markers that can be used to predict cognitive impairment after stroke.
