Influence of perioperative factors on postoperative pulmonary infection in patients with esophageal cancer
- VernacularTitle:食管癌患者术后肺部感染的围术期影响因素分析
- Author:
Yaqun WANG
;
Ling WANG
- Keywords:
Anesthesia factor;
Pulmonary infection;
Esophageal cancer;
Single lung ventilation
- From:
The Journal of Clinical Anesthesiology
2017;33(6):550-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of perioperative factors on postoperative pulmonary infection in patients with esophageal cancer.Methods According to the inclusion criteria in the present study, clinical data of 150 patients undergoing radical prostatectomy for esophageal cancer in our hospital was retrospectively analyzed.In accordance with whether the occurrence of pulmonary infection or not, 32 patients were regarded as pulmonary infection group and 118 patients were designated as no-pulmonary infection group.The dosage of anesthesia drug, intubation time, single lung ventilation time, operation time, anesthesia time, extubation time, intraoperative blood loss, crystal transshipment, colloid transshipment, intraoperative total amount of rehydration, anesthesia methods and one-lung ventilation way were recorded.The indexes of anesthesia factors were compared between the two groups.Multivariable logistic regression analysis was performed to predict the risks of postoperative pulmonary infection for anesthesia factors.Results Total sufentanil and propofol dose, single lung ventilation time, operation time, anesthesia time, extubation time and the percentage of uninterrupted expansion of lung, nose sputum suction catheter and pethidine postoperative analgesia in pulmonary infection group were respectively significantly higher than that of non-pulmonary infection group (all P<0.05).There were no statistical differences of dosage of midazolam and atracurium, intubation time, intraoperative blood loss, crystalloid volume, colloid volume, the total infusion volume, anesthesia methods and intraoperative one-lung ventilation mode between the two groups.Multivariable logistic regression analysis revealed that each increase of sufentanil total dose of 7.5 μg (OR=1.65, 95%CI 1.24-2.85), each increase of 10 min in single lung ventilation time (OR=2.14, 95%CI 1.32-3.62), each increase of 20 min in anesthesia time (OR=1.87, 95%CI 1.46-3.15), nose sputum suction catheter (OR=2.03, 95%CI 1.27-3.46)as well as pethidine postoperative analgesia (OR=3.44, 95%CI 2.25-5.13) were all risk factors for postoperative pulmonary infection (P<0.05).Conclusion Appropriate amount of sufentanil usage reduces single lung ventilation time and anesthesia time as well as implementing fiber bronchoscope for sputum suction, and postoperative use of self-control vein analgesia can decrease the incidence of postoperative pulmonary infection in esophageal cancer patients.
