Effects of nitroglycerine on cooling and rewarming during cardiopulmonary bypass with deep hypothermic circulatory arrest
- VernacularTitle:硝酸甘油对深低温停循环心肺转流降温和复温的影响
- Author:
Yong DAI
;
Yang XIA
;
Xiaoyan WANG
;
Aiai DENG
;
Zhao WANG
- Keywords:
Nitroglycerine;
Cardiopulmonary bypass;
Deep hypothermic circulatory arrest;
Cooling;
Rewarming
- From:
The Journal of Clinical Anesthesiology
2017;33(6):570-572
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the effects of nitroglycerine on cooling and rewarming during cardiopulmonary bypass with deep hypothermic circulatory arrest (DHCAC).Methods Forty-six patients undergoing total aortic arch replacement with DHCAC, 38 males and 8 females, aged 26-74 years, falling into ASA physical status Ⅳ or Ⅴ, were randomly assigned to study group (n=24) and control group (n=22).The same cooling and rewarming methods were implemented in both groups.During cooling and rewarming, the study group received nitroglycerine infusion and the control group normal saline of same volume.The rectum rewarming time, the nasopharyngeal cooling and rewarming time were measured and compared.Results The time of rewarming rectum was significantly shorter in the study group compared to the control group [(104±30) min vs (127±31) min, P<0.05].There was no difference in cooling time , time of rewarming nasopharynx.Conclusion Nitroglycerine shortens the time of rewarming rectum during cardiopulmonary bypass with deep hypothermic circulatory arrest.
