Relationship between Autophagy and Repair of Spinal Cord Injury Based on Pathogenesis of Stasis Obstructing Meridian (review)

VernacularTitle:"基于""瘀阻经络""病机探讨自噬与脊髓损伤修复的关系"
Author: Lingjie WANG ; Xianbing CHEN
Keywords: stasis obstructing meridian pathogenesis; spinal cord injury; repair; cell autophagy; review
From: Chinese Journal of Rehabilitation Theory and Practice 2017;23(6):654-656
CountryChina
Language:Chinese
Abstract: Spinal cord injury is a kind of central nervous system injury disease caused by trauma. It was found that the up-regulation of autophagy after spinal cord injury could promote the repair of spinal cord injury. Under the condition of stress, autophagy can reduce the number of misfolded proteins and damaged organelles in cells to maintain the stability of intracellular environment. Chinese medicine with Huoxue Quyu Tongluo (against stasis obstructing meridian) efficacy has attracted much attention in the treatment of spinal cord injury, which may associate with the role of regulation of autophagy.