Effect of Eradication of Helicobacter Pylori on Non-alcoholic Fatty Liver Disease

VernacularTitle:根除幽门螺杆菌对非酒精性脂肪性肝病的影响
Author: Pengfei ZHANG ; Fengzhi QUAN ; Yan YANG
Keywords: non-alcoholic fatty liver disease; helicobacter pylori; exercise; quadruple therapy
From: Chinese Journal of Rehabilitation Theory and Practice 2017;23(6):725-727
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of eradication of helicobacter pylori (Hp) combined with comprehensive rehabilitation treat-ment on patients with non-alcoholic fatty liver disease (NAFLD). Methods From December, 2015 to April, 2016, 219 patients diagnosed as NAFLD with Hp infection were enrolled, in which 119 patients (observation group) were treated with anti Hp quadruple therapy. They were tested with 13C urea breath test one month after drug withdrawal. The other 100 patients were as control group. The severity of NAFLD was observed with abdominal ultrasound after six months. Results After treatment, Hp was eradicated in 107 cases (90.68%) in the observation group, one dropped out for pulmonary infection. After six months, the severity of NAFLD improved better in the patients eradicated Hp in the observation group than in the control group (χ2=8.397, P<0.05). Conclusion Eradication of Hp combined with comprehensive rehabilita-tion treatment can improve the severity of NAFLD.