Molecular basis for prostate carcinogenesis
10.11817/j.issn.1672-7347.2017.05.017
- VernacularTitle:前列腺癌发生的分子基础
- Author:
Fangzhi CHEN
;
Xiaokun ZHAO
- Keywords:
prostate carcinoma;
molecular basis;
susceptibility gene;
antioncogene;
oncogene
- From:
Journal of Central South University(Medical Sciences)
2017;42(5):581-587
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer is the most prevalent male urogenital malignancy.Androgen deprivation therapy is the principal method for initial treatment for the patients,but the majority of them will eventually develop progressive disease,a status called castration-resistant prostate carcinoma.Lots of susceptibility genes,tumor suppressor genes and oncogenes,and their variations rdevant to the occurrence and development of prostate cancer have been revealed by the studies of molecular oncology.These findings on the molecular basis of prostate carcinogenesis will further improve the strategies on prevention,diagnosis and clinical management for prostate carcinoma.
