Influencing factors for sudden cardiac death in inpatients
- VernacularTitle:住院患者心源性猝死发生的影响因素研究
- Author:
Yu ZHANG
- Keywords:
Death,sudden,cardiac;
Coronary disease;
Myocardial infarction
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2017;26(3):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore influencing factors for sudden cardiac death (SCD) in inpatients.Methods: A total of 124 patients died of heart disease were enrolled.According to SCD or not, they were divided into SCD group (n=65) and non-SCD group (n=59).Clinical data, laboratory examination results, biological rhythm and ECG manifestation at death were compared between two groups.Results: For biological rhythm at death, 41.54% death occurred during 6:01~12:00 in SCD group, which was significantly higher than other time period (P<0.01 all);there was no significant difference in mortality among all time periods in non-SCD group (P>0.05).Compared with non-SCD group, there were significant rise in death proportion in 6:01~12:00 (23.73% vs.41.54%,P=0.007), in levels of creatine kinase [CK, (1140.66±176.63) IU/L vs.(1949.52±2141.22) IU/L], creatine kinase isoenzyme MB [CK-MB, (92.43±28.30) IU/L vs.(175.20±231.44) IU/L] and cardiac troponin I [cTnI, (30.09±34.27) mg/L vs.(44.34±10.60) mg/L], and significant reduction in left ventricular ejection fraction [LVEF, (49.83±11.24)% vs.(37.53±23.11)%] in SCD group, P<0.01 all;in SCD group, SCD caused by coronary heart disease occupied 86.15% (56/65), and myocardial infarction occupied 66.15%(43/65).Conclusion: Coronary heart disease, especially myocardial infarction, is an important factor leading to sudden cardiac death.Detection of CK, CK-MB, cTnI and LVEF levels have important sense for prevention and treatment of sudden cardiac death.
