A retrospective analysis of the pathogens associated with infectious keratitis
10.16718/j.1009-7708.2017.03.007
- VernacularTitle:感染性角膜炎的病原菌谱回顾性分析
- Author:
Hongyun XU
;
Di CHEN
;
Hai LIU
;
Chunlin LIU
;
Hong LI
;
Zhongxian MA
;
Yizheng LI
;
Baorui YANG
;
Wenbo YANG
- Keywords:
infectious keratitis;
pathogen;
filamentous fungus;
distribution
- From:
Chinese Journal of Infection and Chemotherapy
2017;17(3):260-263
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathogens associated with infectious keratitis for early diagnosis and treatment.Methods This study was conducted with the patients with confirmed diagnosis of infectious keratitis in our hospital during the period from January 2011 through December 2015.The specimens from corneal ulcer were subject to bacterial and fungal culture.The pathogens and associated risk factors of infectious keratitis were analyzed retrospectively.Results Of the 1 046 corneal specimens,369 (35.3%) were positive for microorganisms.The most frequently isolated microorganism was fungal species (53.1%),followed by grampositive cocci (31.2%),gram-negative bacilli (11.1%),and gram-positive bacilli (4.6%).Of the fungal strains,most were Fusarium (69.4%),followed by Aspergillus species (21.9%).Coagulase negative Staphylococcus accounted for more than half (50.4%) of the gram positive cocci.Conclusions Infectious keratitis is primarily associated with fungal infection,especially filamentous fungus such as Fusarium.