Optimization of the Water Extraction Technology of Punica granatum Peel and Flowers in Muzha Uighur Medicine Suppository
10.6039/j.issn.1001-0408.2017.22.20
- VernacularTitle:维吾尔药木吒栓中石榴皮和石榴花水提取工艺的优化
- Author:
Honglin TIAN
;
Liang CHEN
;
Yun SUN
;
Jianmei LI
- Keywords:
Muzha suppository;
Punica granatum flowers;
Punica granatum peel;
Extraction technology;
Orthogonal test;
To-tal tannin;
Ellagic acid
- From:
China Pharmacy
2017;28(22):3099-3101
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the water extraction technology of Punica granatum peel and flowers in Muzha supposito-ry. METHODS:Using total tannin,ellagic acid contents as evaluation indexes,extration time,times,the amount of solvents as in-vestigation factors,L9(34)orthogonal test was adopted to optimize the water extraction technology of P. granatum flowers and peel. And verification test was conducted. RESULTS:The optimal extraction technology of total tannin and ellagic acid in P. granatum peel and flowers was as follow as 10-fold water reflux extraction for 3 times with 2 herbs,0.5 h every time. The average content of total tannin and ellagic acid extracted from 3 batches of herbs was 151.69 mg/g (RSD=1.15%,n=3),24.59 mg/g (RSD=1.41%,n=3)in the verification test,respectively. CONCLUSIONS:The optimized extraction technology is stable,feasible,and can be used for extracting the total tannin and ellagic acid in P. granatum peel and flowers.