Optimization of the Processing Technology of Rehmanniae Radix Praeparata by Muti-indexes Integrating Score-Orthogonal Test
10.6039/j.issn.1001-0408.2017.22.26
- VernacularTitle:多指标综合评分正交试验法优化熟地黄的炮制工艺
- Author:
Wanqian TU
;
Zhimin ZHOU
;
Liuji ZHANG
;
Xiaomiao LIU
;
Bao ZHANG
;
Weifeng CUI
;
Kaiyan LI
;
Li ZHOU
- Keywords:
Rehmanniae radix praeparata;
Orthogonal test;
Processing technology;
Muti-indexes;
Comprehensive score
- From:
China Pharmacy
2017;28(22):3121-3124
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the processing technology of rehmanniae radix praeparata. METHODS:Using transfer rates of catalpol,rehmaionoside D,acteoside,isoacteoside,polysaccharide as indexes for comprehensive score,heating tempera-ture(pressure),heating time and heating times as investigating factors,L9(34)orthogonal test was used to optimize the processing technology of rehmanniae radix praeparata,and verification test was conducted. RESULTS:The optimal processing technology of rehmanniae radix praeparata was as follow as heating temperature of 125 ℃,pressure of 150 kPa for twice,2 h every time. The comprehensive scores of 3 batches of samples were 0.6985,0.6755,0.7016 in the verification test,respectively,RSDs were less than 5%(n=3). CONCLUSIONS:Optimized processing technology is simple,stable,feasible,and can provide reference for in-dustrial production of rehmanniae radix praeparata.
