Adult dermatomyositis with gastrointestinal bleeding and perforation:a case report and analysis of literature

VernacularTitle:成年人皮肌炎合并消化道出血和穿孔八例分析
Author: Mengran ZHANG ; Mei ZHANG
Keywords: Dermatomyositis; Adult; Hemorrhage
From: Chinese Journal of Postgraduates of Medicine 2017;40(7):601-603
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features and prognosis of adult dermatomyositis with gastrointestinal bleeding and perforation. Methods The clinical data of a adult dermatomyositis with gastrointestinal bleeding and perforation were retrospectively analyzed. And the clinical characteristics of this patient were analyzed, combined with 7 cases reported in the literature. Results Among the 8 cases, 6 cases were females and 2 cases were males, aged 18 to 63 years. The 5 cases had melena, 3 cases had hematemesis, 3 cases had hematochezia and 1 case had hemoptysis. The main treatment was glucocorticoids, immunosuppressive agent, intravenous immune globulin (IVIG), endoscopic hemostasis and angiographic embolization. Four of the 8 cases died. Conclusions Adult dermatomyositis with gastrointestinal bleeding and perforation is rare, but the condition is dangerous and the mortality is high. Dermatomyositis with early onset of abdominal pain, vomiting, melena should be alert to serious complications such as gastrointestinal bleeding and perforation.