Diagnosis and treatment of granulomatosis with polyangiitis
10.3760/cma.j.issn.1673-4904.2017.07.026
- VernacularTitle:肉芽肿性多血管炎的诊治
- Author:
Yu LIU
- Keywords:
Vasculitis;
Granuloma;
Diagnosis;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2017;40(7):667-669
- CountryChina
- Language:Chinese
-
Abstract:
Granulomatosis with polyangiitis (GPA) is a systemic inflammatory disease characterized by necrotizing granulomatous inflammation and small vessel vasculitis. Upper and/or lower respiratory tract and kidneys are involved mainly. GPA is a rare disease with complicated clinical manifestations, which causes difficulty in making correct diagnosis. GPA is a serious disease, with a nearly always fatal outcome in the absence of treatment. The combination of immunosuppressant drugs and corticosteroids is a standardized treatment for GPA. Treatment is based on two phases known as the induction phase and the maintenance phase. Here, the diagnosis and treatment of GPA are reviewed.
