The clinical and radiographi c characteristics of erosive hand osteoarthritis
10.3760/cma.j.issn.1007-7480.2017.07.006
- VernacularTitle:侵蚀性手骨关节炎的临床及影像学特征分析
- Author:
Xiaoying ZHANG
;
Xin ZHI
;
Rong MU
;
Limin REN
;
Nan WU
;
Yue YANG
;
Yunshan ZHOU
;
Haihong YAO
;
Nan HONG
;
Zhanguo LI
- Keywords:
Osteoarthritis;
Hand bones;
Radiographics;
Cross-sectional study
- From:
Chinese Journal of Rheumatology
2017;21(7):455-460,封3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical and radiographic characteristics and function of erosive hand osteoarthritis (EOA) patients. Methods Data were obtained from 19 patients with EOA, including their social conditions, clinical conditions, radiographic scores and hand function evaluation. The number of hand osteoarthritis (HOA) patients was 312. The control group consisted of non-EOA patients with hand osteoarthritis with a ratio of 4:1 to EOA patients. A non-parameter test analysis was performed. All data were analyzed by SPSS 23.0 statistical analysis, t test, χ2 test, Fisher exact probility and Spearman's correlations analysis were used for statistical analysis. Results Totally data of 19 patients were collected. Eighteen were female. Onset age was (56±8). Average duration was 56 (12~120) months. FIHOA scores of all the EOA patients were at least 5. All the erosions of 39 joints were characteristically central and erosive changes in 7 joints (18%) showed up as gull-wing. Among 39 erosive joints, including 12 (31%) E and 27 (69%) R, 34 (87%) distal interphalangeal joints were involved. Data analysis found out that EOA patients had longer disease duration (Z=2.610, P=0.009), more severe K-L level (44 ±11 vs 26 ±7, t=7.134, P<0.01), higher AUSCAN total score (28±6 vs 21±7, t=3.781, P<0.01) and higher AUSCAN function score (18±6 vs 12±6, t=4.042, P<0.01). The differences of ESR and CRP were not significant between EOA and non-EOA patients. Conclusion Erosions seen in EOA patients are centrally located gull-wing in the DIP joints. EOA patients have longer duration, more severe radiographic damage and worse joint function.
