The fast blood flow density of intermediate choroid in endogenous Cushing syndrome: analysis of optical coherence tomography angiography
10.3760/cma.j.issn.1005-1015.2017.04.017
- VernacularTitle:内源性库欣综合征患者脉络膜大血管层高速血流密度的扫频光源光相干断层扫描血流成像分析
- Author:
Erqian WANG
;
Song XIA
;
Jingyuan YANG
;
Hong DU
;
Donghui LI
;
Youxin CHEN
- Keywords:
Cushing syndrome;
Choroid;
Regional blood flow;
Tomography,optical coherence
- From:
Chinese Journal of Ocular Fundus Diseases
2017;33(4):400-403
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the fast blood flow density (FBFD) of intermediate choroid between endogenous Cushing syndrome (ECS) patients and healthy control subjects.Methods Thirteen eyes of 7 eligible ECS patients (ECS group) and 13 eyes of 7 gender,age,axial length matched healthy volunteers (control group) were enrolled in this study.For each subject,macular radial scan with swept source optical coherence tomography (SS-OCT) was performed and subfoveal choroidal thickness (SCT) was measured.Then 3.0 mm× 3.0 mm macular scan with SS-OCT angiography was performed,and selected blood flow image at intermediate choroid level or 1/2 SCT beneath Bruch membrane.The grayscale images were then binarized for the analysis of FBFD.Results The SCT in ECS group was (394.7±77.7) μm,which was significantly thicker than (332.1 ± 68.1) μm in control group (t=2.923,P=0.008).The FBFD of intermediate choroid in ECS group were (76.35± 14.46)％,which were significantly greater than (63.57± 13.42)％ in control group (t=2.775,P=0.01).Conclusion ECS patients had increased FBFD at intermediate choroid level compared with healthy controls.
