Use of diagnostic vitrectomy in eyes with uveitis of unknown etiology

Haiyan Lin; Rongping Dai; Yannan Lin; Fangtian Dong; Meifen Zhang; Youxin Chen; Hanyi Min; Junjie YE; Weihong YU; Xiao Zhang

Return

Use of diagnostic vitrectomy in eyes with uveitis of unknown etiology

VernacularTitle:65例诊断不明的葡萄膜炎患者玻璃体切割标本检查诊断结果分析
Author: Haiyan LIN ; Rongping DAI ; Yannan LIN ; Fangtian DONG ; Meifen ZHANG ; Youxin CHEN ; Hanyi MIN ; Junjie YE ; Weihong YU ; Xiao ZHANG
Keywords: Uveitis/diagnosis; Endophthalmitis/diagnosis; Lymphoma/diagnosis; Vitrectomy
From: Chinese Journal of Ocular Fundus Diseases 2017;33(4):404-406
CountryChina
Language:Chinese
Abstract: Objective To analyze the results of diagnostic pars plana vitrectomy (PPV) in patients with uveitis of unknown cause.Methods This is a retrospective case series study.Sixty-five patients (67 eyes) with uveitis of unknown cause were enrolled in this study.There were 31 males (32 eyes) and 34 females (35 eyes).The ages were from 6 to 84 years,with the mean age of (55.00± 18.56) years.All eyes were received PPV.Examination of vitreous samples consisted of microbial stains and culture,microbial DNA and antibody detection,cytokine measurement,cytology,flow cytometry and gene rearrangement detection.Results Vitreous analysis was positive in 40 of 67 eyes (59.7％).Positive results indicated bacterial endophthalmitis in 20 of 40 eyes (50.0％),lymphoma in 11 eyes (27.5％),viral IgM and IgG increased significantly in 3 eyes (7.5％),fungal endophthalmitis in 3 eyes (7.5％),IgG of toxocara increased significantly in 2 eyes (5.0％),IgG of toxoplasma Gondii increased significantly in 1 eye (2.5％).Conclusion The diagnostic yield of vitreous samples in uveitis eyes of unknown cause is 59.7％.