Polarization of retinal macrophages and (or) microglial cells and common ocular fundus diseases
10.3760/cma.j.issn.1005-1015.2017.04.031
- VernacularTitle:巨噬细胞和(或)小胶质细胞的极性分化与眼底疾病的相关性研究现状
- Author:
Keran LI
;
Qiaolin LI
;
Qin JIANG
- Keywords:
Macrophages/pathology;
Microglia/pathology;
Retinal diseases/etiology;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2017;33(4):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Retinal macrophages and (or) microglial cells play important roles in regulating inflammation,angiogenesis and tissue repairing,thus affect the development and prognosis of ischemic retinal disease,ocular immune diseases and ocular tumors.Reversing the polarization imbalance of these cells may provide new therapeutic strategies for ischemic retinal disease and ocular immune diseases.The duality of the polarization direction of these cells is still controversial in the inflammatory reaction and pathological angiogenesis of ischemic retinal disease.Meanwhile,the plasticity and diversity of the function need to be further studied and discussed.
