Research progress of programmed cell death 4 in tumors
10.3760/cma.j.issn.1673-422X.2017.07.008
- VernacularTitle:程序性细胞死亡因子4在肿瘤中的研究进展
- Author:
Lili ZHAO
;
Mei ZHANG
;
Yaodong ZHU
- Keywords:
Neoplasms;
Programmed cell death 4
- From:
Journal of International Oncology
2017;44(7):512-515
- CountryChina
- Language:Chinese
-
Abstract:
Programmed cell death 4 (PDCD4) is a newly discovered tumor suppressor gene, whose expression is regulated by methylation of PDCD4 gene and many kinds of microRNAs.Protein of PDCD4 enco-ding can improve the sensitivity of tumor cells to anticancer agents, inhibit tumor development and metastasis process, and play an important role in a variety of tumors.It is expected to be a clinical indicator to determine the prognosis of tumor.
