Expression and significance of tetraspanin in gastric cancer
10.3760/cma.j.issn.1673-422X.2017.07.015
- VernacularTitle:四跨膜蛋白在胃癌中的表达和意义
- Author:
Xiaofei NIE
;
Zhenkang QIU
;
Ning LIU
;
Weiwei QI
;
Aiping DING
;
Wensheng QIU
- Keywords:
Stomach neoplasms;
Prognosis;
Tetraspanins
- From:
Journal of International Oncology
2017;44(7):537-540
- CountryChina
- Language:Chinese
-
Abstract:
Tetraspanins are a class of cell surface glycoproteins that are expressed very broadly, which can form a complex tetraspanins net by combining with many kinds of cell surface molecules such as integrins, signal proteins, growth factors and so on.In recent years, more and more studies suggest that tetraspanins are closely related to the invasion and metastasis of malignancies and show a certain clinical value, which can be used as new diagnosis and prognosis indicators of malignancy.
