Clinical features and outcomes in acute ischemic stroke patients with remote symptomatic intracranial hemorrhage after intravenous thrombolysis
10.3760/cma.j.issn.1673-4165.2017.05.005
- VernacularTitle:静脉溶栓治疗后并发远隔部位有症状颅内出血的急性缺血性卒中患者的临床特征和转归
- Author:
Jinfang ZHOU
;
Wanhua WANG
;
Zhaoxi MA
;
Yan ZHANG
;
Jieming REN
;
Hongzhou WANG
;
Liyun LU
;
Zhicheng BAO
;
Yongjun CAO
;
Qi FANG
- Keywords:
Stroke;
Brain Ischemia;
Thrombolytic Therapy;
Tissue Plasminogen Activator;
Cerebral Hemorrhage;
Treatment Outcome
- From:
International Journal of Cerebrovascular Diseases
2017;25(5):412-415
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate clinical features and outcomes in acute ischemic stroke patients with remote symptomatic intracranial hemorrhage (sICHr) after intravenous thrombolysis.MethodsThe acute ischemic stroke patients with sICHr after intravenous thrombolysis therapy were enrolled retrospectively.The clinical data were collected and the related literature was analyzed and summarized.ResultsA total of 6 acute ischemic stroke patients with sICHr were enrolled, including 4 males.Three patients had a history of using antiplatelet agents, 2 with atrial fibrillation, 4 with hypertension, 3 with previous stroke history, 4 with smoking history, and 4 had sICHr at 2 h after intravenous thrombolysis.Of the 14 hemorrhagic foci (except in the infarct areas), 10 were in the cerebral cortex.Three patients died within 1 week, and 1 was in a persistent vegetative state.Conclusions SICHr after intravenous thrombolysis in patients with acute ischemic stroke is mainly located in the cerebral cortex.The outcomes in acute ischemic stroke patients with SICHr after intravenous thrombolysis are poor, and the mortality is high.
