Common complications and mechanisms of urinary system after hematopoietic stem cell transplantation in children
10.3760/cma.j.issn.1673-4408.2017.07.004
- VernacularTitle:儿童造血干细胞移植后泌尿系统常见并发症及机制
- Author:
Ruyue CHEN
- Keywords:
National Natural Science Foundation of China(81370787);
The Jiangsu Province Clinical Medical Science and Technology Commission(SBL2014030237).
- From:
International Journal of Pediatrics
2017;44(7):456-459
- CountryChina
- Language:Chinese
-
Abstract:
Hematopoietic stem cell transplantation(HSCT)is an important treatment of various hematological diseases,and urinary system injury is one of the common complications after HSCT,including acute renal damage,chronic kidney disease,nephrotic syndrome after transplantation,transplantation associated thrombotic microangiopathy,urinary tract infection,hemorrhagic cystitis,etc.The etiology includes three aspects:prerenal,renal and postrenal.Various factors have interactions with each other.The clinical manifestations,treatment and prognosis are different due to the disease types and severity.Renal biopsy is of great significance for the etiological analysis,therapeutic guide and prognostic vaule.This article reviews the common complications and mechanisms of urinary system after HSCT in children.
