Application of real-time continuous glucose monitoring in outpatient management system for type 1 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2017.05.002
- VernacularTitle:实时动态血糖监测在1型糖尿病门诊管理体系中的应用
- Author:
Yanjun SHEN
;
Yaqiang TIAN
;
Ming LI
;
Ying LI
;
Honggang DUAN
;
Lanbo PENG
;
Shaoxia LU
;
Xiaoqin TIAN
;
Xinchen LI
- Keywords:
Real-time continuous glucose monitoring system;
Diabetes mellitus;
type 1;
Outpatient management system;
Control status;
Economic burden of disease
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(5):367-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of continuous glucose monitoring system(CGMS) in improving the current status of type 1 diabetes mellitus(T1DM) control and reducing the economic burden of the patients.Methods One hundred and fifteen patients with T1DM were randomly assigned to the CGMS group and the self-monitoring of blood glucose(SMBG) group respectively.The patients in CGMS group were on 72 h CGMS every 6 months, while SMBG group only with SMBG to guide the insulin dose adjustment.The levels of blood glucose and the statistics of the number of hypoglycemia and diabetic ketoacidosis were taken as the main observational indexes every 6 months.The chronic complication and the statistics of the number of hospitalizations and the total cost of treatment were made as the secondary observational index every 12 months.Results 2 h postprandial plasma glucose(2hPG) and mean blood glucose(MBG) in the CGMS group were lower than those in the SMBG group [(10.7±1.9 vs 11.5±2.7) mmol/L, (9.7±0.5 vs 10.6±0.7) mmol/L, P<0.05] in the clinical follow-up visit after 6 months.The per capita number of hypoglycaemia in the CGMS group was lower than that in the SMBG group[(7.9±2.6 vs 9.2±3.4) times, P<0.05].In the outpatient follow-up re-visit to the patients after 6 months, fasting plasma glucose(FPG), 2hPG, MBG, and HbA1C of the patients in the CGMS group were lower than those in the SMBG group(t=4.71~9.75, P<0.05), the per capita numbers of hypoglycemia and DKA in the CGMS group were lower than those in the SMBG group(t=3.61~4.37, P<0.05).Conclusion The application of real-time continuous glucose monitoring in T1DM outpatient management may reduce the whole-day blood glucose of the patients, decrease the incidence risk of hypoglycemia, and improve the compliance of the treatment while without increasing the economic burden of the disease.
