Progress of methotrexate combined with other drugs for treatment of primary central nervous system lymphoma
10.3760/cma.j.issn.1009-9921.2017.06.016
- VernacularTitle:甲氨蝶呤联合其他药物治疗原发中枢神经系统淋巴瘤研究进展
- Author:
Lu ZHANG
- Keywords:
Lymphoma;
Central nervous system;
Methotrexate;
Drug therapy,combination
- From:
Journal of Leukemia & Lymphoma
2017;26(6):375-379
- CountryChina
- Language:Chinese
-
Abstract:
Primary central nervous system lymphoma (PCNSL) is a rare type of extranodal lymphoma, and its incidence rate is increasing nowadays. Chemotherapy is the main means for treatment of PCNSL and the efficacy of high-dose methotrexate (HD-MTX) has been confirmed among those chemotherapeutics. Treatments of HD-MTX combined with other drugs have been studied extensively. Progress of HD-MTX and other drugs for PCNSL are reviewed in this article.