Relationship between eosinophil count and intracranial aneurysm

VernacularTitle:嗜酸粒细胞与颅内动脉瘤的相关性
Author: Jun DU ; Yonghong WANG ; Yongqiang LI ; Xiaonan FAN
Keywords: intracranial aneurysm; eosinophil; inflammation; leukocyte
From: Journal of Xi'an Jiaotong University(Medical Sciences) 2017;38(4):622-624,封3
CountryChina
Language:Chinese
Abstract: Objective To assess the relationship between eosinophil count and intracranial aneurysm (IA).Methods For the retrospective study,we collected data of the count of eosinophils obtained from the peripheral blood samples and other clinical data of 79 patients with IA admitted to our hospital between January 2014 and December 2015 and 65 healthy people as control group.Risk factors for IA were analyzed by multivariate Logistics regression analysis.Results Clinical characteristics were comparable between the two groups (P＞0.05).Compared with those in the control group,eosinophil and platelet counts in IA group were significantly higher [(0.18±0.12)109/L vs.(0.12±0.09)109/L;(196.44±57.33)109/L vs.(178.80±47.23)109/L,respectively;all P＜0.05],while platelet distribution width (PDW) and mean platelet volume (MPV) were lower [(13.95 ± 3.332)fL vs.(15.30±3.5)fL;(11.02±1.73)fL vs.(11.66±1.31)fL,respectively;all P＜0.05].Logistic regression analysis indicated that eosinophil was the independent risk factor for IA.Corclusion Our study demonstrated that increased eosinophil count is the independent risk factor for IA.