Research progress of receptor tyrosine kinase AXL in tumor
10.11904/j.issn.1002-3070.2017.03.019
- VernacularTitle:受体酪氨酸激酶AXL在肿瘤中的研究进展
- Author:
Xiaosong TANG
- Keywords:
Receptor tyrosine kinase;
AXL;
Tumor;
AXL kinase inhibitors
- From:
Practical Oncology Journal
2017;31(3):281-284
- CountryChina
- Language:Chinese
-
Abstract:
AXL is a member of the TAM receptor tyrosine kinase family,and AXL has been shown to beassociated with a variety of cancers such as lung cancer,breast cancer,thyroid cancer,prostate cancer and pancre-atic cancer.The latest evidence suggests that AXL can promote the growth,invasion and metastasis of varioustumors,and its inhibitors can also inhibit tumor formation,suggesting that AXL may be a potential target for anti-tumor therapy,and the use of AXL kinase inhibitors may become the new strategy of anti-tumor therapy.This ar-ticle reviews the progress of AXL and tumor.
