Research progress of matrix protein in bone metastasis of malignant tumor
10.11904/j.issn.1002-3070.2017.03.020
- VernacularTitle:基质蛋白对恶性肿瘤骨转移作用的研究进展
- Author:
Lizhi JIAN
;
Tianjiao WAGN
- Keywords:
Matrix proteins;
Bone marrow matrix;
Bone metastases
- From:
Practical Oncology Journal
2017;31(3):285-288
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of bone metastases in malignant tumors is high,and seriously affected the lifequality of patients.It is clear that the mechanism of the prevention and treatment of malignant tumors are of greatsignificance.It has been confirmed that tumor microenvironment plays an important role in the migration of prima-ry tumors,and the matrix protein is an important component of bone marrow microenvironment.In recent years,thelatest study has been found that matrix proteins can be involved in the process of bone metastasis by promotingtumor cell proliferation,invasion and metastasis.In this paper,the role of matrix proteins in the process of bonemetastasis of malignant tumors was reviewed.
