Modified Yupingfeng Powder in Adjuvant Therapy of Allergic Rhinitis:A Systematic Review
10.6039/j.issn.1001-0408.2017.21.19
- VernacularTitle:玉屏风散加减辅助治疗过敏性鼻炎的系统评价
- Author:
Wei GUO
;
Yingxian HE
;
Xuwen ZHANG
;
Junmao WEN
;
Yude LIU
- Keywords:
Yupingfeng powder;
Allergic rhinitis;
Meta-analysis;
Systermatic review;
Efficacy;
Safety
- From:
China Pharmacy
2017;28(21):2947-2950
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To systematically evaluate therapeutic efficacy and safety of Yupingfeng powder in adjavant therapy of allergic rhinitis,and to provide evidence-based reference for clinical treatment. METHODS:Retrieved from Wanfang database,VIP,CJFD,CBM,Cochrane Library,EMBase and PubMed,RCTs about Yupingfeng powder combined with chemical medicine (trial group)vs. chemical medicine alone in the treatment of allergic rhinitis were collected. Meta-analysis was conducted by using Rev Man 5.2 statistical software after data extraction and quality evaluation according to Cochrane system evaluation method 5.1.0. RESULTS:A total of 15 RCTs were included,invovling 1366 patients. The results of Meta analysis showed that response rate [OR=3.95,95%CI(2.80,5.58),P<0.001],recurrence rate [OR=0.37,95%CI(0.22,0.63),P<0.001] and the incidence of ADR [OR=0.15,95%CI(0.06,0.35),P<0.001] in trial group were significantly higher than control group,with statistical significance. CONCLUSIONS:Yupingfeng powder in adjuvant therapy of allergic rhinitis show good therapeutic efficacy and can reduce recur-rence rate with good safety.