Effects of dopamine and norepinephrine on blood oxygen,heart rate and internal environment in patients with septic shock

VernacularTitle:多巴胺与去甲肾上腺素配合使用对感染性休克患者血氧、心率及内环境的影响
Author: Qinjuan QIAN ; Hong DONG ; Zhiyong FEI
Keywords: Dopamine; Norepinephrine; Infection; Shock
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(17):2620-2622
CountryChina
Language:Chinese
Abstract: Objective To analyze the effects of dopamine and norepinephrine on blood oxygen,heart rate and internal environment in patients with septic shock.Methods 80 patients with septic shock were collected.The patients were randomly divided into two groups.The control group was given dopamine treatment,the observation group was given dopamine and norepinephrine.Results The heart rate (HR)[(90.39±15.29)/min],ScVO2 index[(77.03±7.68)％] of the observation group were better than those of the control group (t=4.122 5,2.141 5,all P＜0.05).The urine volume[(94.05±22.39)mL/h],creatinine clearance rate[(53.12±14.45)mL/min] of the observation group were better than those of the control group (t=3.660 6,2.023 2,all P＜0.05).ConclusionDopamine combined with norepinephrine has significant effect on patients with septic shock,which can effectively improve the HR,ScVO2,urine volume,creatinine clearance rate and other indicators,thus to restore the patients'' internal environment.