Septic disseminated intravascular coagulation: Mechanisms and monitoring
10.16571/j.cnki.1008-8199.2017.07.006
- VernacularTitle:脓毒症合并弥散性血管内凝血的机制与监测
- Author:
Jingchun SONG
- Keywords:
Sepsis;
Disseminated intravascular coagulation;
Thromboelastography
- From:
Journal of Medical Postgraduates
2017;30(7):703-708
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis-induced disseminated intravascular coagulation (DIC) is a severe and relatively common disorder with high mortality in intensive care units.Sepsis at the early stage is usually manifested as hypercoagulable, while septic DIC as hypocoagulable.This article focuses on the pathophysiological mechanisms of septic DIC in the aspects up-regulation of procoagulant pathways, impairment of physiological anticoagulant mechanism, and suppression of fibrinolysis.It also gives a brief introduction to the application of thromboelastography in the diagnosis of septic DIC.
