Application of UTMD mediated microRNA transfection in disease treatment
10.16571/j.cnki.1008-8199.2017.07.021
- VernacularTitle:UTMD介导microRNA转染在疾病治疗中的应用研究
- Author:
Yao MA
- Keywords:
Ultrasound-targeted microbubble destruction;
MicroRNA;
Transfection
- From:
Journal of Medical Postgraduates
2017;30(7):780-784
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, research about microRNA has been increasing.How to safely and effectively introduce microRNA into target cells and target tissues is the key to successful treatment of diseases using microRNA.Many studies have reported that ultrasound-targeted microbubble destruction technology (UTMD) mediated gene transfection has the advantages of safety, targeting and high transfection efficiency.The research of UTMD mediated microRNA transfection has also increased year by year.The mechanism of UTMD mediated microRNA transfection and the application in the treatment of diseases such as cancer and cardiovascular system are reviewed in this paper.